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High-throughput, fluorescent-aptamer-based measurements of steady-state transcription rates for Mycobacterium tuberculosis RNA polymerase

The first step in gene expression is the transcription of DNA sequences into RNA. Regulation at the level of transcription leads to changes in steady-state concentrations of RNA transcripts, affecting the flux of downstream functions and ultimately cellular phenotypes. Changes in transcript levels a...

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Detalles Bibliográficos
Autores principales: Jensen, Drake, Manzano, Ana Ruiz, Rector, Maxwell, Tomko, Eric J., Record, M. Thomas, Galburt, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054983/
https://www.ncbi.nlm.nih.gov/pubmed/36993414
http://dx.doi.org/10.1101/2023.03.13.532464