Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans: a target for novel antifungals

Invasive fungal diseases are a major threat to human health, resulting in more than 1.5 million deaths worldwide each year. Yet the arsenal of antifungal therapeutics remains limited and is in dire need of novel drugs that target additional fungal-specific biosynthetic pathways. One such pathway inv...

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Detalles Bibliográficos
Autores principales: Washington, Erica J., Zhou, Ye, Hsu, Allen L., Petrovich, Matthew, Borgnia, Mario J., Bartesaghi, Alberto, Brennan, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054996/
https://www.ncbi.nlm.nih.gov/pubmed/36993618
http://dx.doi.org/10.1101/2023.03.14.530545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054996/
https://www.ncbi.nlm.nih.gov/pubmed/36993618
http://dx.doi.org/10.1101/2023.03.14.530545

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