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The Development of Cell-Penetrating Peptides for Efficient and Selective In Vivo Expression of mRNA in Spleen Tissue

mRNA-based therapeutics are presently one of the nucleic acid-based therapeutics with a high potential for extraordinary success as preventive vaccines. Current applications with mRNA therapeutics rely on lipid nanoparticle (LNP) mediated delivery of nucleic acids. In order to achieve the transition...

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Detalles Bibliográficos
Autores principales: Porosk, Ly, Härk, Heleri Heike, Arukuusk, Piret, Haljasorg, Uku, Peterson, Pärt, Kurrikoff, Kaido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055000/
https://www.ncbi.nlm.nih.gov/pubmed/36986813
http://dx.doi.org/10.3390/pharmaceutics15030952