An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction

Great efforts are being made to develop advanced polygenic risk scores (PRS) to improve the prediction of complex traits and diseases. However, most existing PRS are primarily trained on European ancestry populations, limiting their transferability to non-European populations. In this article, we pr...

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Detalles Bibliográficos
Autores principales: Zhang, Jingning, Zhan, Jianan, Jin, Jin, Ma, Cheng, Zhao, Ruzhang, O’ Connell, Jared, Jiang, Yunxuan, Koelsch, Bertram L., Zhang, Haoyu, Chatterjee, Nilanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055041/
https://www.ncbi.nlm.nih.gov/pubmed/36993331
http://dx.doi.org/10.1101/2023.03.15.532652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055041/
https://www.ncbi.nlm.nih.gov/pubmed/36993331
http://dx.doi.org/10.1101/2023.03.15.532652

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