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An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction
Great efforts are being made to develop advanced polygenic risk scores (PRS) to improve the prediction of complex traits and diseases. However, most existing PRS are primarily trained on European ancestry populations, limiting their transferability to non-European populations. In this article, we pr...
Autores principales: | Zhang, Jingning, Zhan, Jianan, Jin, Jin, Ma, Cheng, Zhao, Ruzhang, O’ Connell, Jared, Jiang, Yunxuan, Koelsch, Bertram L., Zhang, Haoyu, Chatterjee, Nilanjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055041/ https://www.ncbi.nlm.nih.gov/pubmed/36993331 http://dx.doi.org/10.1101/2023.03.15.532652 |
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