Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2

A wide range of endogenous and xenobiotic organic ions require facilitated transport systems to cross the plasma membrane for their disposition(1,2). In mammals, organic cation transporter subtypes 1 and 2 (OCT1 and OCT2, also known as SLC22A1 and SLC22A2, respectively) are polyspecific transporters...

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Detalles Bibliográficos
Autores principales: Suo, Yang, Wright, Nicholas J., Guterres, Hugo, Fedor, Justin G., Butay, Kevin John, Borgnia, Mario J., Im, Wonpil, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055046/
https://www.ncbi.nlm.nih.gov/pubmed/36993738
http://dx.doi.org/10.1101/2023.03.15.532610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055046/
https://www.ncbi.nlm.nih.gov/pubmed/36993738
http://dx.doi.org/10.1101/2023.03.15.532610

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