N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters

Antigen-induced B-cell receptor (BCR) signaling is critical for initiating and regulating B-cell activation. The actin cytoskeleton plays essential roles in BCR signaling. Upon encountering cell-surface antigens, actin-driven B-cell spreading amplifies signaling, while B-cell contraction following s...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhanja, Anshuman, Seeley-Fallen, Margaret K., Lazzaro, Michelle, Upadhyaya, Arpita, Song, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055065/
https://www.ncbi.nlm.nih.gov/pubmed/36993351
http://dx.doi.org/10.1101/2023.03.14.532631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055065/
https://www.ncbi.nlm.nih.gov/pubmed/36993351
http://dx.doi.org/10.1101/2023.03.14.532631

Ejemplares similares