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N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters
Antigen-induced B-cell receptor (BCR) signaling is critical for initiating and regulating B-cell activation. The actin cytoskeleton plays essential roles in BCR signaling. Upon encountering cell-surface antigens, actin-driven B-cell spreading amplifies signaling, while B-cell contraction following s...
Autores principales: | Bhanja, Anshuman, Seeley-Fallen, Margaret K., Lazzaro, Michelle, Upadhyaya, Arpita, Song, Wenxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055065/ https://www.ncbi.nlm.nih.gov/pubmed/36993351 http://dx.doi.org/10.1101/2023.03.14.532631 |
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