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Growth-dependent gene expression variation influences the strength of codon usage biases

The most highly expressed genes in microbial genomes tend to use a limited set of synonymous codons, often referred to as “preferred codons.” The existence of preferred codons is commonly attributed to selection pressures on various aspects of protein translation including accuracy and/or speed. How...

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Detalles Bibliográficos
Autores principales: Johnson, Mackenzie M., Hockenberry, Adam J., McGuffie, Matthew J., Vieira, Luiz Carlos, Wilke, Claus O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055066/
https://www.ncbi.nlm.nih.gov/pubmed/36993177
http://dx.doi.org/10.1101/2023.03.14.532645