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Shared gene targets of the ATF4 and p53 transcriptional networks

The master tumor suppressor p53 regulates multiple cell fate decisions, like cell cycle arrest and apoptosis, via transcriptional control of a broad gene network. Dysfunction in the p53 network is common in cancer, often through mutations that inactivate p53 or other members of the pathway. Inductio...

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Detalles Bibliográficos
Autores principales: Baniulyte, Gabriele, Durham, Serene A., Merchant, Lauren E., Sammons, Morgan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055071/
https://www.ncbi.nlm.nih.gov/pubmed/36993734
http://dx.doi.org/10.1101/2023.03.15.532778