Rapid and accurate deorphanization of ligand-receptor pairs using AlphaFold

Secreted proteins are extracellular ligands that play key roles in paracrine and endocrine signaling, classically by binding cell surface receptors. Experimental assays to identify new extracellular ligand-receptor interactions are challenging, which has hampered the rate of novel ligand discovery....

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Detalles Bibliográficos
Autores principales: Danneskiold-Samsøe, Niels Banhos, Kavi, Deniz, Jude, Kevin M., Nissen, Silas Boye, Wat, Lianna W., Coassolo, Laetitia, Zhao, Meng, Santana-Oikawa, Galia Asae, Broido, Beatrice Blythe, Garcia, K. Christopher, Svensson, Katrin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055078/
https://www.ncbi.nlm.nih.gov/pubmed/36993313
http://dx.doi.org/10.1101/2023.03.16.531341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055078/
https://www.ncbi.nlm.nih.gov/pubmed/36993313
http://dx.doi.org/10.1101/2023.03.16.531341

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