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Elastin-like polypeptide delivery of anti-inflammatory peptides to the brain following ischemic stroke

Inflammatory processes are activated following ischemic strokes and lead to increased tissue damage for weeks following the ischemic insult, but there are no approved therapies that target this inflammation-induced secondary injury. Here, we report that SynB1-ELP-p50i, a novel protein inhibitor of t...

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Detalles Bibliográficos
Autores principales: Howell, John Aaron, Gaouette, Nicholas, Lopez, Mariper, Burke, Stephen P., Perkins, Eddie, Bidwell, Gene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055169/
https://www.ncbi.nlm.nih.gov/pubmed/36993686
http://dx.doi.org/10.1101/2023.03.15.532834