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Can a bulky glycocalyx promote catch bonding in early integrin adhesion? Perhaps a bit
Many types of cancer overexpress bulky glycoproteins to form a thick glycocalyx layer. The glycocalyx physically separates the cell from its surroundings, but recent work has shown that the glycocalyx can paradoxically increase adhesion to soft tissues and therefore promote the metastasis of cancer...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055170/ https://www.ncbi.nlm.nih.gov/pubmed/36993661 http://dx.doi.org/10.1101/2023.03.16.532909 |