Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells

The protein diversity of mammalian cells is determined by arrays of isoforms from genes. Genetic mutation is essential in species evolution and cancer development. Accurate Long-read transcriptome sequencing at single-cell level is required to decipher the spectrum of protein expressions in mammalia...

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Detalles Bibliográficos
Autores principales: Liu, Silvia, Yu, Yan-Ping, Ren, Bao-Guo, Ben-Yehezkel, Tuval, Obert, Caroline, Smith, Mat, Wang, Wenjia, Ostrowska, Alina, Soto-Gutierrez, Alejandro, Luo, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055174/
https://www.ncbi.nlm.nih.gov/pubmed/36993628
http://dx.doi.org/10.1101/2023.03.16.532991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055174/
https://www.ncbi.nlm.nih.gov/pubmed/36993628
http://dx.doi.org/10.1101/2023.03.16.532991

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