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Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells
The protein diversity of mammalian cells is determined by arrays of isoforms from genes. Genetic mutation is essential in species evolution and cancer development. Accurate Long-read transcriptome sequencing at single-cell level is required to decipher the spectrum of protein expressions in mammalia...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055174/ https://www.ncbi.nlm.nih.gov/pubmed/36993628 http://dx.doi.org/10.1101/2023.03.16.532991 |