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Changes in Environmental Stress over COVID-19 Pandemic Likely Contributed to Failure to Replicate Adiposity Phenotype Associated with Krtcap3

We previously identified Keratinocyte-associated protein 3, Krtcap3, as an obesity-related gene in female rats where a whole-body Krtcap3 knock-out (KO) led to increased adiposity compared to wild-type (WT) controls when fed a high-fat diet (HFD). We sought to replicate this work to better understan...

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Detalles Bibliográficos
Autores principales: Szalanczy, Alexandria M, Giorgio, Gina, Goff, Emily, Seshie, Osborne, Grzybowski, Michael, Klotz, Jason, Geurts, Aron M, Redei, Eva E, Solberg Woods, Leah C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055176/
https://www.ncbi.nlm.nih.gov/pubmed/36993361
http://dx.doi.org/10.1101/2023.03.15.532439