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Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in db/db mice

Endothelial cells play a key role in maintaining homeostasis and are deranged in many disease processes, including fibrotic conditions. Absence of the endothelial glucocorticoid receptor (GR) has been shown to accelerate diabetic kidney fibrosis in part through up regulation of Wnt signaling. The db...

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Detalles Bibliográficos
Autores principales: Srivastava, Swayam Prakash, Goodwin, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055184/
https://www.ncbi.nlm.nih.gov/pubmed/36993478
http://dx.doi.org/10.1101/2023.03.20.533532