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Quantification of elongation stalls and impact on gene expression in yeast

Ribosomal pauses are a critical part of co-translational events including protein folding and localization. However, extended ribosome pauses can lead to ribosome collisions, resulting in the activation of ribosome rescue pathways and turnover of protein and mRNA. While this relationship has been kn...

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Detalles Bibliográficos
Autores principales: Hou, Wanfu, Harjono, Vince, Harvey, Alex T., Subramaniam, Arvind Rasi, Zid, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055187/
https://www.ncbi.nlm.nih.gov/pubmed/36993688
http://dx.doi.org/10.1101/2023.03.19.533377