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Compartment-Specific Activation of the Proton-Sensor GPR65 is Uncoupled from Receptor Trafficking
The canonical view of G protein-coupled receptor (GPCR) function is that receptor trafficking is tightly coupled to signaling. GPCRs remain on the plasma membrane (PM) at the cell surface until they are activated, after which they are desensitized and internalized into endosomal compartments. This c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055196/ https://www.ncbi.nlm.nih.gov/pubmed/36993269 http://dx.doi.org/10.1101/2023.03.18.533272 |