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Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

The energy-burning capability of beige adipose tissue is a potential therapeutic tool for reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we evaluate the impact of aging on the profile and activity of adipocyte stem and progenitor cells (ASPCs) and adipocytes d...

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Detalles Bibliográficos
Autores principales: Holman, Corey D., Sakers, Alexander P., Calhoun, Ryan P., Cheng, Lan, Fein, Ethan C., Jacobs, Christopher, Tsai, Linus, Rosen, Evan D., Seale, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055201/
https://www.ncbi.nlm.nih.gov/pubmed/36993336
http://dx.doi.org/10.1101/2023.03.20.533514