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Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
The energy-burning capability of beige adipose tissue is a potential therapeutic tool for reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we evaluate the impact of aging on the profile and activity of adipocyte stem and progenitor cells (ASPCs) and adipocytes d...
Autores principales: | Holman, Corey D., Sakers, Alexander P., Calhoun, Ryan P., Cheng, Lan, Fein, Ethan C., Jacobs, Christopher, Tsai, Linus, Rosen, Evan D., Seale, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055201/ https://www.ncbi.nlm.nih.gov/pubmed/36993336 http://dx.doi.org/10.1101/2023.03.20.533514 |
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