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HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages
The HIV-1 accessory protein, Vpr, is an enigmatic protein required for efficient spread of HIV from macrophages to T cells, a necessary step for propagation of infection. To illuminate the role of Vpr in HIV-infection of primary macrophages, we used single-cell RNA sequencing to capture the transcri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055223/ https://www.ncbi.nlm.nih.gov/pubmed/36993393 http://dx.doi.org/10.1101/2023.03.21.533528 |