HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages

The HIV-1 accessory protein, Vpr, is an enigmatic protein required for efficient spread of HIV from macrophages to T cells, a necessary step for propagation of infection. To illuminate the role of Vpr in HIV-infection of primary macrophages, we used single-cell RNA sequencing to capture the transcri...

Descripción completa

Detalles Bibliográficos
Autores principales: Virgilio, Maria C., Disbennett, W. Miguel, Chen, Thomas, Lubow, Jay, Welch, Joshua D., Collins, Kathleen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055223/
https://www.ncbi.nlm.nih.gov/pubmed/36993393
http://dx.doi.org/10.1101/2023.03.21.533528

Ejemplares similares

Ejemplares similares