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A beneficial adaptive role for CHOP in driving cell fate selection during ER stress

Cellular stresses elicit signaling cascades that are capable of either mitigating the inciting dysfunction or initiating cell death. During endoplasmic reticulum (ER) stress, the transcription factor CHOP is widely recognized to promote cell death. However, it is not clear whether CHOP also has a be...

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Detalles Bibliográficos
Autores principales: Liu, Kaihua, Zhao, Chaoxian, Adajar, Reed C., DeZwaan-McCabe, Diane, Rutkowski, D. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055232/
https://www.ncbi.nlm.nih.gov/pubmed/36993175
http://dx.doi.org/10.1101/2023.03.19.533325