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Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet

Advances in single-cell and -nucleus transcriptomics have enabled generation of increasingly large-scale datasets from hundreds of subjects and millions of cells. These studies promise to give unprecedented insight into the cell type specific biology of human disease. Yet performing differential exp...

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Detalles Bibliográficos
Autores principales: Hoffman, Gabriel E., Lee, Donghoon, Bendl, Jaroslav, Fnu, Prashant, Hong, Aram, Casey, Clara, Alvia, Marcela, Shao, Zhiping, Argyriou, Stathis, Therrien, Karen, Venkatesh, Sanan, Voloudakis, Georgios, Haroutunian, Vahram, Fullard, John F., Roussos, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055252/
https://www.ncbi.nlm.nih.gov/pubmed/36993704
http://dx.doi.org/10.1101/2023.03.17.533005