The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans

SET-26, HCF-1, and HDA-1 are highly conserved chromatin factors with key roles in development and aging. Here we present mechanistic insights into how these factors regulate gene expression and modulate longevity in C. elegans. We show that SET-26 and HCF-1 cooperate to regulate a common set of gene...

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Detalles Bibliográficos
Autores principales: Emerson, Felicity J., Chiu, Caitlin, Lin, Laura Y., Riedel, Christian G., Zhu, Ming, Lee, Siu Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055255/
https://www.ncbi.nlm.nih.gov/pubmed/36993207
http://dx.doi.org/10.1101/2023.03.20.531974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055255/
https://www.ncbi.nlm.nih.gov/pubmed/36993207
http://dx.doi.org/10.1101/2023.03.20.531974

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