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Protein supersaturation powers innate immune signaling

The response of cells to existential threats such as virus invasion often involves semi-crystalline polymerization of certain signaling proteins, but the highly ordered nature of the polymers has no known function. We hypothesized that the undiscovered function is kinetic in nature, emerging from th...

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Detalles Bibliográficos
Autores principales: Rodriguez Gama, Alejandro, Miller, Tayla, Lange, Jeffrey J., Wu, Jianzheng, Song, Xiaoqing, Venkatesan, Shriram, Unruh, Jay R., Bradford, Dan, Halfmann, Randal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055258/
https://www.ncbi.nlm.nih.gov/pubmed/36993308
http://dx.doi.org/10.1101/2023.03.20.533581