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Intermediate antiparallel fibrils in Aβ40 Dutch mutant aggregation: nanoscale insights from AFM-IR

Cerebral Amyloid Angiopathy (CAA), which involves amyloid deposition in blood vessels leading to fatal cerebral hemorrhage and recurring strokes, is present in the majority Alzheimer’s disease cases. Familial mutations in the amyloid β peptide is correlated to higher risks of CAA, and are mostly com...

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Detalles Bibliográficos
Autores principales: Banerjee, Siddhartha, Naik, Tanmayee, Ghosh, Ayanjeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055286/
https://www.ncbi.nlm.nih.gov/pubmed/36993390
http://dx.doi.org/10.1101/2023.03.21.533667