Distinct Transcriptomic Responses to Aβ plaques, Neurofibrillary Tangles, and APOE in Alzheimer’s Disease

INTRODUCTION: Omics studies have revealed that various brain cell types undergo profound molecular changes in Alzheimer’s disease (AD) but the spatial relationships with plaques and tangles and APOE-linked differences remain unclear. METHODS: We performed laser capture microdissection of Aβ plaques,...

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Detalles Bibliográficos
Autores principales: Das, Sudeshna, Li, Zhaozhi, Wachter, Astrid, Alla, Srinija, Noori, Ayush, Abdourahman, Aicha, Tamm, Joseph A., Woodbury, Maya E., Talanian, Robert V., Biber, Knut, Karran, Eric H., Hyman, Bradley T., Serrano-Pozo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055287/
https://www.ncbi.nlm.nih.gov/pubmed/36993332
http://dx.doi.org/10.1101/2023.03.20.533303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055287/
https://www.ncbi.nlm.nih.gov/pubmed/36993332
http://dx.doi.org/10.1101/2023.03.20.533303

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