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Visualization of translation reorganization upon persistent collision stress in mammalian cells

Aberrantly slow mRNA translation leads to ribosome stalling and subsequent collision with the trailing neighbor. Ribosome collisions have recently been shown to act as stress sensors in the cell, with the ability to trigger stress responses balancing survival and apoptotic cell-fate decisions depend...

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Detalles Bibliográficos
Autores principales: Fedry, Juliette, Silva, Joana, Vanevic, Mihajlo, Fronik, Stanley, Mechulam, Yves, Schmitt, Emmanuelle, des Georges, Amédée, Faller, William, Förster, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055323/
https://www.ncbi.nlm.nih.gov/pubmed/36993420
http://dx.doi.org/10.1101/2023.03.23.533914