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Visualization of translation reorganization upon persistent collision stress in mammalian cells
Aberrantly slow mRNA translation leads to ribosome stalling and subsequent collision with the trailing neighbor. Ribosome collisions have recently been shown to act as stress sensors in the cell, with the ability to trigger stress responses balancing survival and apoptotic cell-fate decisions depend...
Autores principales: | Fedry, Juliette, Silva, Joana, Vanevic, Mihajlo, Fronik, Stanley, Mechulam, Yves, Schmitt, Emmanuelle, des Georges, Amédée, Faller, William, Förster, Friedrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055323/ https://www.ncbi.nlm.nih.gov/pubmed/36993420 http://dx.doi.org/10.1101/2023.03.23.533914 |
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