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Adaptive therapy for ovarian cancer: An integrated approach to PARP inhibitor scheduling

Toxicity and emerging drug resistance are important challenges in PARP inhibitor (PARPi) treatment of ovarian cancer. Recent research has shown that evolutionary-inspired treatment algorithms which adapt treatment to the tumor’s treatment response (adaptive therapy) can help to mitigate both. Here,...

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Detalles Bibliográficos
Autores principales: Strobl, Maximilian, Martin, Alexandra L., West, Jeffrey, Gallaher, Jill, Robertson-Tessi, Mark, Gatenby, Robert, Wenham, Robert, Maini, Philip, Damaghi, Mehdi, Anderson, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055330/
https://www.ncbi.nlm.nih.gov/pubmed/36993591
http://dx.doi.org/10.1101/2023.03.22.533721