Cargando…

B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model

Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription factor STAT3. To better understand the role of STAT3 during gammaherpesvirus latency and immune control, we utilized murine...

Descripción completa

Detalles Bibliográficos
Autores principales: Hogan, Chad H., Owens, Shana M., Reynoso, Glennys V., Kirillov, Varvara, Meyer, Thomas J., Zelazowska, Monika A., Liu, Bin, Li, Xiaofan, Chikhalya, Aniska, Dong, Qiwen, Khairallah, Camille, Reich, Nancy C., Sheridan, Brian, McBride, Kevin M., Hearing, Patrick, Hickman, Heather D., Forrest, J. Craig, Krug, Laurie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055336/
https://www.ncbi.nlm.nih.gov/pubmed/36993230
http://dx.doi.org/10.1101/2023.03.22.533727