Testing a polygenic risk score for morphological microglial activation in Alzheimer’s disease and aging

Neuroinflammation and the activation of microglial cells are among the earliest events in Alzheimer’s disease (AD). However, direct observation of microglia in living people is not currently possible. Here, we indexed the heritable propensity for neuroinflammation with polygenic risk scores (PRS), u...

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Detalles Bibliográficos
Autores principales: Tio, Earvin S., Hohman, Timothy J., Milic, Milos, Bennett, David A., Felsky, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055438/
https://www.ncbi.nlm.nih.gov/pubmed/36993775
http://dx.doi.org/10.1101/2023.03.10.23287119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055438/
https://www.ncbi.nlm.nih.gov/pubmed/36993775
http://dx.doi.org/10.1101/2023.03.10.23287119

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