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Porcine Reproductive and Respiratory Syndrome Virus Engineered by Serine Substitution on the 44th Amino Acid of GP5 Resulted in a Potential Vaccine Candidate with the Ability to Produce High Levels of Neutralizing Antibody

SIMPLE SUMMARY: The slow and weak formation of neutralizing antibodies against the PRRSV is related to the N-linked glycosylation site surrounding the major epitope in the ectodomain of GP5 protein. To develop vaccine candidates that induce high levels of neutralizing antibodies, various previous st...

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Detalles Bibliográficos
Autores principales: Choi, Jong-Chul, Kim, Min-Sik, Choi, Hwi-Yeon, Kang, Yeong-Lim, Choi, In-Yeong, Jung, Sung-Won, Jeong, Ji-Yun, Kim, Min-Chul, Cho, Andrew Y., Lee, Ji-Ho, Lee, Dong-Hun, Lee, Sang-Won, Park, Seung-Yong, Song, Chang-Seon, Choi, In-Soo, Lee, Joong-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055445/
https://www.ncbi.nlm.nih.gov/pubmed/36977230
http://dx.doi.org/10.3390/vetsci10030191