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Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism

Extracellular vesicles (EVs) derived from mesenchymal stem/stromal cells (MSCs) have recently been widely explored in clinical trials for treatment of diseases with complex pathophysiology. However, production of MSC EVs is currently hampered by donor-specific characteristics and limited ex vivo exp...

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Detalles Bibliográficos
Autores principales: Levy, Daniel, Abadchi, Sanaz Nourmohammadi, Shababi, Niloufar, Ravari, Mohsen Rouhani, Pirolli, Nicholas H., Bergeron, Cade, Obiorah, Angel, Mokhtari-Esbuie, Farzad, Gheshlaghi, Shayan, Abraham, John M., Smith, Ian M., Powsner, Emily, Solomon, Talia, Harmon, John W., Jay, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055496/
https://www.ncbi.nlm.nih.gov/pubmed/36993554
http://dx.doi.org/10.1101/2023.03.19.533334