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Long noncoding RNA Malat1 inhibits Tead3-Nfatc1–mediated osteoclastogenesis to suppress osteoporosis and bone metastasis

MALAT1, one of the few highly conserved nuclear long noncoding RNAs (IncRNAs), is abundantly expressed in normal tissues. Previously, targeted inactivation and genetic rescue experiments identified MALAT1 as a suppressor of breast cancer lung metastasis. On the other hand, Malat1-knockout mice are v...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Teng, Hongqi, Deng, Yalan, Sheldon, Marisela, Martinez, Consuelo, Zhang, Jie, Tian, Annie, Sun, Yutong, Nakagawa, Shinichi, Yao, Fan, Wang, Hai, Ma, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055520/
https://www.ncbi.nlm.nih.gov/pubmed/36993303
http://dx.doi.org/10.21203/rs.3.rs-2405644/v1