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Peptide derived from progranulin of the carcinogenic liver fluke, Opisthorchis viverrini stimulates cell hyperproliferation and proinflammatory cytokine production

PURPOSE: Progranulin (PGRN) is a secreted glycoprotein growth factor with roles in wound healing, inflammation, angiogenesis and malignancy. An orthologue of the gene encoding human PGRN was identified in the carcinogenic liver fluke Opisthorchis viverrini. METHODS: Sequence structure, general chara...

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Detalles Bibliográficos
Autores principales: Hembasat, Thanapat, Chaiyadet, Sujittra, Ittiprasert, Wannaporn, Smout, Michael J, Young, Neil D, Loukas, Alex, Brindley, Paul J, LAHA, THEWARACH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055533/
https://www.ncbi.nlm.nih.gov/pubmed/36993607
http://dx.doi.org/10.21203/rs.3.rs-2586058/v1