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Minimal mechanistic component of HbYX-dependent proteasome activation

The implication of reduced proteasomal function in neurodegenerative diseases combined with numerous studies showing the protective effects of increasing proteasome activity in animal models justify the need to understand how the proteasome is activated for protein degradation. The C-terminal HbYX m...

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Detalles Bibliográficos
Autores principales: Chuah, Janelle J., Thibaudeau, Tiffany A., Rexroad, Matthew S., Smith, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055539/
https://www.ncbi.nlm.nih.gov/pubmed/36993338
http://dx.doi.org/10.21203/rs.3.rs-2496767/v1