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Organoid modeling reveals the tumorigenic potential of the alveolar progenitor cell state

Alveolar type 2 (AT2) cells, the epithelial progenitor cells of the distal lung, are known to be the prominent cell of origin for lung adenocarcinoma. The regulatory programs that control chromatin and gene expression in AT2 cells during the early stages of tumor initiation are not well understood....

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Detalles Bibliográficos
Autores principales: Li, Jingyun, Dang, Susanna M., Schurmann, Paul, Dost, Antonella F.M., Moye, Aaron L., Paschini, Margherita, Bhetariya, Preetida J, Bronson, Roderick, Sui, Shannan J. Ho, Kim, Carla F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055547/
https://www.ncbi.nlm.nih.gov/pubmed/36993454
http://dx.doi.org/10.21203/rs.3.rs-2663901/v1