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Type I interferon-dependent IFIT3 signaling is critical for viral clearance in airway neutrophils

Neutrophilic inflammation characterizes several respiratory viral infections including COVID-19-related ARDS, although its contribution to disease pathogenesis remains poorly understood. Here, we identified two neutrophil subpopulations (A1 and A2) in the airway compartment of 52 severe COVID-19 sub...

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Detalles Bibliográficos
Autores principales: Margaroli, Camilla, Fram, Timothy, Sharma, Nirmal S., Patel, Siddharth B., Tipper, Jennifer, Robison, Sarah W., Russell, Derek W., Fortmann, Seth D., Banday, Mudassir M., Abdalla, Tarek, Saitornuang, Sawanan, Madison, Matthew C., Leal, Sixto M., Harrod, Kevin S., Erdmann, Nathaniel B., Gaggar, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055555/
https://www.ncbi.nlm.nih.gov/pubmed/36993474
http://dx.doi.org/10.21203/rs.3.rs-1812836/v1