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Rapid emergence and transmission of virulence-associated mutations in the oral poliovirus vaccine following vaccination campaigns
There is an increasing burden of circulating vaccine-derived polioviruses (cVDPVs) due to the continued use of oral poliovirus vaccine (OPV). However, the informativeness of routine OPV VP1 sequencing for the early identification of viruses carrying virulence-associated reversion mutations has not b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055580/ https://www.ncbi.nlm.nih.gov/pubmed/36993386 http://dx.doi.org/10.1101/2023.03.16.23287381 |