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Acute pharmacodynamic responses to exenatide: Drug-induced increases in insulin secretion and glucose effectiveness

BACKGROUND: GLP1R agonists provide multiple benefits to patients with type 2 diabetes – including improved glycemic control, weight loss, and decreased risk of major adverse cardiovascular events. Because drug responses vary among individuals, we initiated investigations to identify genetic variants...

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Detalles Bibliográficos
Autores principales: Taylor, Simeon I., Montasser, May E., Yuen, Ashley H., Fan, Hubert, Yazdi, Zhinoosossadat Shahidzadeh, Whitlatch, Hilary B., Mitchell, Braxton D., Shuldiner, Alan R., Muniyappa, Ranganath, Streeten, Elizabeth A., Beitelshees, Amber L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055582/
https://www.ncbi.nlm.nih.gov/pubmed/36993363
http://dx.doi.org/10.1101/2023.03.15.23287166