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Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection

The impact of previous SARS-CoV-2 infection on the durability of Ad26.COV2.S vaccine-elicited responses, and the effect of homologous boosting has not been well explored. We followed a cohort of healthcare workers for 6 months after receiving the Ad26.COV2.S vaccine and a further one month after the...

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Detalles Bibliográficos
Autores principales: Moyo-Gwete, Thandeka, Richardson, Simone I., Keeton, Roanne, Hermanus, Tandile, Spencer, Holly, Manamela, Nelia P., Ayres, Frances, Makhado, Zanele, Motlou, Thopisang, Tincho, Marius B., Benede, Ntombi, Ngomti, Amkele, Baguma, Richard, Chauke, Masego V., Mennen, Mathilda, Adriaanse, Marguerite, Skelem, Sango, Goga, Ameena, Garrett, Nigel, Bekker, Linda-Gail, Gray, Glenda, Ntusi, Ntobeko A.B., Riou, Catherine, Burgers, Wendy A., Moore, Penny L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055608/
https://www.ncbi.nlm.nih.gov/pubmed/36993404
http://dx.doi.org/10.1101/2023.03.15.23287288