CYP2E1 overexpression protects COS-7 cancer cells against ferroptosis

Ferroptosis is a recently described form of regulated cell death initiated by the iron-mediated one-electron reduction of lipid hydroperoxides (LOOH). Cytochrome P450 2E1 (CYP2E1) induction, a consequence of genetic polymorphisms or/and gene induction by xenobiotics, may promote ferroptosis by contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Caro, Andres A., Barrett, Daniel, Garcia, Cristobal, Northington, Weston, Pinkney, Jamya, Shuja, Rayan, Stovall, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055644/
https://www.ncbi.nlm.nih.gov/pubmed/36993697
http://dx.doi.org/10.21203/rs.3.rs-2702878/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055644/
https://www.ncbi.nlm.nih.gov/pubmed/36993697
http://dx.doi.org/10.21203/rs.3.rs-2702878/v1

Ejemplares similares