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Formal synthesis of kibdelomycin and derivatisation of amycolose glycosides
A convergent total synthesis of bacterial gyrase B/topoisomerase IV inhibitor kibdelomycin (a.k.a. amycolamicin) (1) was devised starting from inexpensive d-mannose and l-rhamnose, which were converted in new efficient ways to an N-acylated amycolose and an amykitanose derivative as late building bl...
Autores principales: | Schriefer, Manuel G., Treiber, Laura, Schobert, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055692/ https://www.ncbi.nlm.nih.gov/pubmed/37006682 http://dx.doi.org/10.1039/d3sc00595j |
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