Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green

Technology for generating especially important amide and peptide bonds from carboxylic acids and amines that avoids traditional coupling reagents is described. The 1-pot processes developed rely on thioester formation, neat, using a simple dithiocarbamate, and are safe and green, and rely on Nature-...

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Detalles Bibliográficos
Autores principales: Freiberg, Kaitlyn M., Kavthe, Rahul D., Thomas, Rohan M., Fialho, David M., Dee, Paris, Scurria, Matthew, Lipshutz, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055766/
https://www.ncbi.nlm.nih.gov/pubmed/37006678
http://dx.doi.org/10.1039/d3sc00198a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055766/
https://www.ncbi.nlm.nih.gov/pubmed/37006678
http://dx.doi.org/10.1039/d3sc00198a

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