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Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green
Technology for generating especially important amide and peptide bonds from carboxylic acids and amines that avoids traditional coupling reagents is described. The 1-pot processes developed rely on thioester formation, neat, using a simple dithiocarbamate, and are safe and green, and rely on Nature-...
Autores principales: | Freiberg, Kaitlyn M., Kavthe, Rahul D., Thomas, Rohan M., Fialho, David M., Dee, Paris, Scurria, Matthew, Lipshutz, Bruce H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055766/ https://www.ncbi.nlm.nih.gov/pubmed/37006678 http://dx.doi.org/10.1039/d3sc00198a |
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