Immunomodulatory Activity of the Tyrosine Kinase Inhibitor Dasatinib to Elicit NK Cytotoxicity against Cancer, HIV Infection and Aging

Tyrosine kinase inhibitors (TKIs) have been extensively used as a treatment for chronic myeloid leukemia (CML). Dasatinib is a broad-spectrum TKI with off-target effects that give it an immunomodulatory capacity resulting in increased innate immune responses against cancerous cells and viral infecte...

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Detalles Bibliográficos
Autores principales: Rodríguez-Agustín, Andrea, Casanova, Víctor, Grau-Expósito, Judith, Sánchez-Palomino, Sonsoles, Alcamí, José, Climent, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055786/
https://www.ncbi.nlm.nih.gov/pubmed/36986778
http://dx.doi.org/10.3390/pharmaceutics15030917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055786/
https://www.ncbi.nlm.nih.gov/pubmed/36986778
http://dx.doi.org/10.3390/pharmaceutics15030917

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