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Immunomodulatory Activity of the Tyrosine Kinase Inhibitor Dasatinib to Elicit NK Cytotoxicity against Cancer, HIV Infection and Aging
Tyrosine kinase inhibitors (TKIs) have been extensively used as a treatment for chronic myeloid leukemia (CML). Dasatinib is a broad-spectrum TKI with off-target effects that give it an immunomodulatory capacity resulting in increased innate immune responses against cancerous cells and viral infecte...
Autores principales: | Rodríguez-Agustín, Andrea, Casanova, Víctor, Grau-Expósito, Judith, Sánchez-Palomino, Sonsoles, Alcamí, José, Climent, Núria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055786/ https://www.ncbi.nlm.nih.gov/pubmed/36986778 http://dx.doi.org/10.3390/pharmaceutics15030917 |
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